Piperine: a Valuable
نویسندگان
چکیده
The present scientific peer review describes on novel natural cyclobutane characterization of this alkaloid showed that it an efficient bioavailability enhancer for different anti-cancer, anti-depressant, anti-apoptotic, anti extraction, quantification and applications of piperine we substantial knowledge to scientific world to develop industries.
منابع مشابه
Effects of 7-Week Aerobic Training and Piperine Supplementation on Oxidative Stress Markers of Brain Tissue in Male Wistar Rats Exposed to Paraquat
Introduction: Paraquat triggers oxidative stress and apoptosis. This study aimed to explore the effects of 7-week aerobic training and piperine supplementation on oxidative stress markers of brain tissue in male Wistar rats exposed to paraquat. Materials and Methods: Forty-eight adult rats were divided into 6 groups: 1) sham, 2) paraquat (negative control), 3) paraquat+training, 4) paraquat+tra...
متن کاملThe Potency of Piperine as Antiinflammatory and Analgesic
The potency of piperine as anti inflammatory and analgesic were investigated. Piperine was evaluated for antiinflammatory effect by carrageen-induced rat paw edema. Sprague Dawley Rats were divided into the control groups were given saline perorally, piperine groups received doses of 2.5; 5 and 10 mg/kg piperine (peroral) respectively. This was followed by the administration of 1 % caragenin th...
متن کاملPiperine Causes G1 Phase Cell Cycle Arrest and Apoptosis in Melanoma Cells through Checkpoint Kinase-1 Activation
In this study, we determined the cytotoxic effects of piperine, a major constituent of black and long pepper in melanoma cells. Piperine treatment inhibited the growth of SK MEL 28 and B16 F0 cells in a dose and time-dependent manner. The growth inhibitory effects of piperine were mediated by cell cycle arrest of both the cell lines in G1 phase. The G1 arrest by piperine correlated with the dow...
متن کاملPharmacokinetic Interaction between Magnolol and Piperine in Rats
Purpose: To investigate the pharmacokinetic mechanism of interaction between magnolol and piperine when co-administered to rats. Methods: The rats were divided into five groups as follows: magnolol group (625 mg/kg); low dose of piperine group (20 mg/kg); high dose of piperine group (40 mg/kg); low dose of piperine + magnolol group; or high dose of piperine + magnolol group. Plasma samples were...
متن کاملDocking studies of piperine - iron conjugate with human CYP450 3A4
Piperine, a major constituent of Piper nigrum (Black pepper), is one of the well known components in many Ayurvedic formulations. Piperine is most studied bioenhancer because it inhibits drug metabolizing enzymes in rodents and increases plasma concentrations of several drugs, including P-glycoprotein substrates. However, there areno evidences on piperine-iron conjugate to inhibit human CYP450 ...
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